Blog
NAD+ and aging: The coenzyme your mitochondria are running out of
NAD+ levels drop by 50% by age 40 and fuel every cellular repair process. Learn why NAD+ declines, how it drives aging, and 7 evidence-based ways to restore it.
NMN vs NR: Which NAD+ precursor actually works for longevity?
NMN and NR both boost NAD+ levels, but they differ in absorption, tissue distribution, and clinical evidence. Compare the science behind each precursor.
Rapamycin and mTOR inhibition: The most promising anti-aging drug?
Rapamycin extends lifespan in every species tested. Learn how mTOR inhibition works, what the PEARL trial revealed, and whether low-dose rapamycin is ready for human use.
Senolytics: Can clearing zombie cells actually reverse aging?
Senescent 'zombie' cells accumulate with age and drive inflammation, disease, and biological aging. Learn how senolytics work and what the science actually shows.
Acetylcholine and aging: Why your memory neurotransmitter declines and how to protect it
Acetylcholine supports memory, attention, sleep, and vagal tone. Learn what changes with age, how choline intake matters, and safer ways to track it.
Andropause: Male hormonal decline and what to do about it
Andropause describes age-related male hormone decline. Learn symptoms, testing, lifestyle levers, and when to discuss testosterone deficiency with a clinician.
Antibiotics and aging: How medications disrupt your longevity microbiome
Learn how antibiotics can disrupt the gut microbiome, what recovery can look like, and how to support resilience without avoiding needed treatment.
Cortisol awakening response: What your morning stress spike reveals about aging
The cortisol awakening response shows how morning cortisol rises after waking. Learn normal CAR patterns, testing limits, stress links, and practical habits.
Dopamine and aging: Why motivation fades and how to restore it
Dopamine receptors and transporters decline with age. Learn how that affects motivation, reward, movement and the habits that support brain aging.