Blog
Hearing loss and cognitive decline: the underrated connection that accelerates aging
Hearing loss is the #1 modifiable risk factor for dementia. Learn how untreated hearing loss accelerates brain aging and what you can do to protect your cognition.
Pharmacogenomics and aging: why the same drug works differently after 50
Drug metabolism declines 30% after 70 and varies by genotype. Learn how pharmacogenomics, CYP450 enzymes, and aging interact to affect medication safety and effectiveness.
Polygenic risk scores: predicting disease risk from DNA
Polygenic risk scores combine thousands of genetic variants to predict disease risk. Learn how PRS works, what it reveals about longevity, and its current limitations.
Serotonin and aging: why mood regulation gets harder after 40
Serotonin receptors decline 10-15% per decade after 40. Learn why mood regulation gets harder with age and how to protect your serotonin system for longevity.
Alzheimer's prevention: 14 modifiable risk factors that account for 45% of cases
The 2024 Lancet Commission identifies 14 modifiable dementia risk factors. Learn which ones can be changed to help protect long-term brain health.
Cancer and aging: why risk rises after 50
Cancer risk rises with age as DNA damage, immune surveillance, inflammation, and tissue context change. Learn screening and prevention steps that reduce risk.
Chronic kidney disease: the aging organ nobody monitors
CKD is often silent until advanced stages. Learn how eGFR, creatinine, cystatin C, and urine albumin reveal kidney aging and cardiovascular risk.
Fatty liver disease and metabolic aging: MASLD markers and what helps
MASLD and fatty liver can signal metabolic risk before symptoms. Learn the current terminology, useful lab markers, FIB-4 context, and lifestyle levers.
Osteoporosis and bone aging: DEXA scans, prevention, and what you can actually reverse
Bone density peaks at 30 and declines steadily after. Learn how DEXA scores work, which exercises build bone, and how to prevent osteoporosis after 40.